What Is Macular Degeneration?

Macular Degeneration

Macular degeneration is an eye disease that impacts central vision, meaning individuals with this disease have difficulty seeing things directly in front of them. This condition is commonly associated with aging and typically affects those over 50.

It specifically affects the macula, which is the central part of the retina located at the back of the eye. The retina is responsible for controlling central vision. While macular degeneration impairs central vision, it does not lead to complete blindness. People with this condition still retain their peripheral vision, allowing them to see objects off to the sides.

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Age-Related Macular Degeneration (AMD)

Dry Macular Degeneration

  • What It Is: This is the most common type of macular degeneration. It happens slowly over time as the cells in the macula break down and lose their function.
  • What Happens: Small yellow deposits called drusen build up under the retina, causing the macula to deteriorate gradually. This leads to a gradual loss of central vision, making it harder to read, recognize faces, or see fine details.
  • Progression: It tends to progress slowly and may not cause severe vision loss in its early stages.

Wet Macular Degeneration

  • What It Is: This is less common but more serious. It occurs when new, abnormal blood vessels grow under the retina and leak fluid or blood.
  • What Happens: The leakage causes rapid damage to the macula, leading to sudden or severe loss of central vision. You might notice distorted vision or dark spots in your central vision.
  • Progression: It can progress quickly and can cause more significant vision loss compared to dry macular degeneration.

Summary

  • Dry: Slow and gradual loss of vision due to the breakdown of macula cells.
  • Wet: Fast and severe vision loss caused by leaking blood vessels under the retina.

Both types can impact your vision, but wet macular degeneration often requires more urgent treatment to manage and slow down the vision loss. If you’re concerned about macular degeneration or notice changes in your vision, it's important to consult an eye care professional for a thorough examination and appropriate management.

Management and Treatment

How is macular degeneration managed or treated?

Currently, there is no cure for macular degeneration. However, early treatment can help slow the progression of the disease and reduce the severity of symptoms. Even with effective treatments, symptoms may return. Treatment options vary based on the type of macular degeneration and can include nutritional supplements, medications, photodynamic therapy (PDT), and laser therapy.

Nutritional supplements for dry age-related macular degeneration (AMD)

Research from the Age-Related Eye Disease Studies (AREDS and AREDS2) suggests that a specific combination of vitamins and minerals can help slow the progression of dry AMD. These supplements typically include:

  • Vitamin C
  • Vitamin E
  • Lutein
  • Zinc
  • Copper
  • Zeaxanthin

The original AREDS formula contained beta-carotene, which posed a risk of lung cancer for smokers and former smokers. The updated AREDS2 formula replaced beta-carotene with lutein and zeaxanthin.

Medications for wet age-related macular degeneration (AMD)

While there are no drugs that cure wet AMD, certain medications can help manage it. Anti-vascular endothelial growth factor (anti-VEGF) injections are commonly used. These injections block VEGF, a protein that stimulates the growth of abnormal blood vessels in the eye. Typically administered by a retina specialist, these injections are given directly into the vitreous (intravitreal injections) and can sometimes improve vision.

The Statistics

There are various risk factors associated with this eye disease like smoking, over-exposure to ultra-violet rays and obesity. Statistically, Caucasians are at a significantly greater risk than African Americans for contracting macular degeneration. Genetically, this disease affects women in greater numbers than men.

Overall, there is no cure or outright prevention of macular degeneration other than living a healthy lifestyle and maintaining regular eye examinations. The best one can do is to detect the disease early and follow the instructions of your optometrist to manage the progress of the disease.

If you would like a consultation on macular degeneration, as well as other diseases and conditions that affect the eyes, then please contact the eye care professionals at Total Vision Centers, located in Springboro, where new patients are always welcome.